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HIV Drug Combo Shown Not Effective at Treating Novel Coronavirus COVID-19

No benefit observed with lopinavir–ritonavir treatment.

Clinical trial of lopinavir-ritonavir (brand name: Kaletra) shows no benefit beyond standard of care for patients with severe novel coronavirus infection

As the search continues for treatments, cure, or vaccine for novel coronavirus (COVID-19) continues, a new article published on March 18, 2020, in the New England Journal of Medicine says that a two HIV drug combo of lopinavir-ritonavir (brand name: Kaletra) fails to provide benefit beyond standard of care in trial.

“In hospitalized adult patients with severe Covid-19, no benefit was observed with lopinavir–ritonavir treatment beyond standard care. Future trials in patients with severe illness may help to confirm or exclude the possibility of a treatment benefit.”

Full article available here: https://www.nejm.org/doi/full/10.1056/NEJMoa2001282

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